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Re: German trying to use PT to lower Lp(a) without success

Posted: Tue Jul 14, 2020 7:58 am
by Frodo
pamojja wrote:
Frodo wrote:This does not correspond to the Pauling/Rath therapy.


I'm 53 and it does correspont to the Linus Pauling therapy. Rath's therapy is very different and uses only tiny doses in comparison.

https://patents.google.com/patent/US5278189A/en

SUMMARY OF THE INVENTION

The foregoing needs in the treatment and prevention of cardiovascular disease are met by the methods and compositions of the present invention.

A method is provided for the treatment of occlusive cardiovascular disease, comprising the step of administering to a subject an effective amount of ascorbate and one or more binding inhibitors, as a mixture or as a compound comprising ascorbate covalently linked with binding inhibitors, which inhibit the binding of Lp(a) to blood vessel walls, such as arterial walls. This effect may also be obtained by administering an effective amount of one or more inhibitors, without ascorbate. The term binding inhibitor throughout the specification and claims is intended to include all substances that have an affinity for the lysine binding site present on the interior walls of blood vessels, particularly arteries, the site of Lp(a) binding. Most of these substances compete with plasmin for the lysine binding site and some of these compounds, in high doses, are in clinical use for the treatment of hyperfibrinolytic states.


Even if it doesn't lower Lp(a), it still inhibits the binding of Lp(a) to blood vessel walls. Theoretically.

Practically I experienced a remission from a 60% walking-disablity due to PAD, a 80% stenosis at my abdominal aorta bifurcation. As unexpected side-effects further remissions: COPD, T2D, NAFLD, CKD, ME/CFS..[/

That is indeed a whole range of diseases. But I miss your heart. How is your heart disease diagnosed? Do you have stents or bypasses? Or is it ok?

Re: German trying to use PT to lower Lp(a) without success

Posted: Tue Jul 14, 2020 8:10 am
by Frodo
pamojja
I probably made a mistake when posting. But I think you see my question.

Re: German trying to use PT to lower Lp(a) without success

Posted: Tue Jul 14, 2020 1:06 pm
by pamojja
I had cardio-vascular-disease (CVD) by way of PAD diagnosed. Not by a narrowing of heart-arteries, but at the abdominal aorta bifurcation.

Peripheral artery disease (PAD) is one kind of CVD, as is heart-disease and stroke. Though a brain MRI did show an old stroke in my cerebellium, that must have occured as a toddler, since I don't remember having experienced any of its symptoms. No narrowing of heart arteries in my case. Though I did experience angina-like chestpains, they went away simply by using enough CoQ10. MDs sure wanted to replace my aorta down my legs with a synthetic goretex-like Y-shaped prosthesis. I thought that's utterly crazy, before trying other non-invasive means. Would think the same of stents or bypasses, if still conscious.

One can have it only in the perphery, or the heart, or the brain. Or a mix of those. But not neccesarily.

However, I think better to let this completely hilarious endless off-topic thread die. The title is a contratiction itself, since Pauling therapy also works without lowering Lp(a), already expained in Pauling's patent. I usually don't read here, only did because you requested by PM yesterday.

Re: German trying to use PT to lower Lp(a) without success

Posted: Thu Jul 16, 2020 5:33 am
by Frodo

Re: German trying to use PT to lower Lp(a) without success

Posted: Fri Jul 17, 2020 8:39 am
by Frodo

Re: German trying to use PT to lower Lp(a) without success

Posted: Sat Jul 18, 2020 2:54 am
by Frodo
I will do my lp(a) check not until next week. Because again I missed to drink enough and then my blood becomes too thick. As I noticed, this increases the measured value. I have also found that a limitation of the glomular filtration rate (GFR) is associated with an increased plasma concentration of lp(a) (I read it in Austrian Journal of Cardiology, 2015; 22 (5-6), 115-118, and have tested it). This also depends on the fluid intake.

Re: German trying to use PT to lower Lp(a) without success

Posted: Sat Jul 18, 2020 7:15 am
by Frodo

Re: German trying to use PT to lower Lp(a) without success

Posted: Wed Jul 22, 2020 3:28 am
by Frodo

Re: German trying to use PT to lower Lp(a) without success

Posted: Sat Jul 25, 2020 2:54 am
by Frodo

Re: German trying to use PT to lower Lp(a) without success

Posted: Wed Aug 05, 2020 8:50 am
by Frodo

Re: German trying to use PT to lower Lp(a) without success

Posted: Mon Aug 10, 2020 4:28 am
by Frodo
An interesting article by Dr. Andrew Saul. Always worth reading. www.doctoryourself.com/niacin.html (Dr. Saul wrote about it on Facebook).
According to Dr. Hoffer, I take it immediately after finishing a meal and together with flush free niacin (contains niacin and inositol). And a glass of water. Mostly that helps.

Re: German trying to use PT to lower Lp(a) without success

Posted: Thu Aug 13, 2020 3:38 am
by Frodo

Re: German trying to use PT to lower Lp(a) without success

Posted: Thu Aug 13, 2020 9:01 am
by DiverDown2
Got my LP-a test results back today:
Lipoprotein (a) = 204.9 High nmol/L <75.0
Last time it was 175, time before that it was 224.
It seems no matter what I do nothing works, so I just keep taking PT at max. dosage.
If anyone has some answers, please Post.

Re: German trying to use PT to lower Lp(a) without success

Posted: Thu Aug 13, 2020 9:52 am
by Frodo
Look at my post 428. How many niacin and proline do you take? And did you drink enough before?
But also look at my post 430 and my questions.

Re: German trying to use PT to lower Lp(a) without success

Posted: Thu Aug 13, 2020 11:09 am
by DiverDown2
You could really be on to something, with Niacin and Proline.
I only take 200mg. niacin and 1.2 Grams proline, looking back when my LP-a dropped to 175 I was taking 2 Grams proline.
So I will increase L-Proline to 3 Grams, and try to get my Niacin intake up, the Flush is awful.
yes I always hydrate before blood draw.

My question is inflammation the cause of high LP-a ?