Brilinta and Olive Oil

[DiverDown2]

Is it ok to consume Olive Oil while on Brilinta?

[pamojja]

I would take up to 4 tablespoons of organic olive oil a day, and drop the brilinta. Why? Because there is a very good website called http://www.thennt.com which evaluated all major studies for common CVD prescriptions for their actual risk/benefit ratios.

These were the drugs and interventions prescribed to me, and after being informed, refused all of them:

Statins Given for 5 Years for Heart Disease Prevention (With Known Heart Disease)

83 for mortality

In Summary, for those who took the statin for 5 years:

Benefits in NNT

1 in 83 were helped (life saved)
1 in 39 were helped (preventing non-fatal heart attack)
1 in 125 were helped (preventing stroke)

Harms in NNH

1 in 100 were harmed (develop diabetes*)
1 in 10 were harmed (muscle damage)

*The development of diabetes is one such unanticipated harm found in a recent large study and it seems likely therefore that this applies to the data above, although this is a best guess.


Aspirin to Prevent Cardiovascular Disease in Patients with Known Heart Disease or Strokes

333 for mortality

In Summary, for those who took the aspirin:

Benefits in NNT

1 in 50 were helped (cardiovascular problem prevented)
1 in 333 were helped (prevented death)
1 in 77 were helped (prevented non-fatal heart attack)
1 in 200 were helped (prevented non-fatal stroke)

Harms in NNH

1 in 400 were harmed (major bleeding event*)

*Required hospital admission and transfusion



Blood Pressure Medicines for Five Years to Prevent Death, Heart Attacks, and Strokes

125 for mortality

In Summary, for those who took anti-hypertensives:

Benefits in NNT

1 in 125 were helped (prevented death)
1 in 67 were helped (prevented stroke)
1 in 100 were helped (prevented heart attack*)

Harms in NNH

1 in 10 were harmed (medication side effects, stopping the drug)

*fatal and non-fatal myocardial infarction and sudden or rapid cardiac death



Clopidogrel Added to Aspirin to Prevent a Second Heart Attack Or Stroke

None for mortality

In Summary, for those who took the clopidogrel:

Benefits in NNT

None were helped (cardiovascular problem prevented)

Harms in NNT

1 in 167 were harmed (major bleeding event*)



Coronary Stenting for Non-Acute Coronary Disease Compared to Medical Therapy

None for mortality

In Summary, for those who received the stenting:

Benefits in NNT

None were helped (life saved, heart attack prevented, symptoms reduced)

Harms in NNH

1 in 50 were harmed (complications such as bleeding, stroke, kidney damage)

NNT = the number needed to treat. In the case of statins that means out of 83 patients with prior heart-attack taking statins (for primary prevention these numbers turn astronomical) after 5 years only for one of them a premature death is prevented. There are no dependable longer term studies.

NNH = the number needed to harm. Note, there aren't any numbers for mortality available. But we know that prescription drugs along with malpractice is the 3th most cause of death, right after CVD and cancer.

The risk/benefit ratio for Brilinta = Ticagrelor

Ticagrelor Compared to Clopidogrel in Acute Coronary Syndrome and Stable Coronary Artery Disease

None for mortality

In summary, for patients who received ticagrelor:

Benefits in NNT

No patients were helped

Harms in NNT

1 in 166 patients had a major bleeding event
1 in 13 patients developed dyspnea

Same as Clopidogrel: no patient were helped!

Decide wisely.