Magnesium May Slow Atherosclerosis

[Seymore Spectacles]

This was a study done on HD patients, who appear to be at higher risk of heart disease. Still, it would seem plausible that magnesium deficiency, in general, could play a role in increased atherosclerosis in non-HD patients as well.

Magnesium supplementation helps to improve carotid intima media thickness in patients on hemodialysis.

Turgut F, Kanbay M, Metin MR, Uz E, Akcay A, Covic A.

Department of Internal Medicine, Section of Nephrology, Fatih University School of Medicine, Hosdere cad no:145, Y. Ayranci, 06540, Ankara, Turkey, turgutfaruk@yahoo.com.

BACKGROUND: The atherosclerotic process progresses more dynamically in hemodialysis (HD) patients than in the general population. In HD patients, lower magnesium levels were reported to be associated with increased atherosclerosis of the common carotid artery. We tested the hypotheses that magnesium supplementation helps to improve carotid intima media thickness (IMT) in HD patients.

MATERIALS AND METHODS: A total of 47 patients on HD were included in the study. Patients were randomly divided into two groups: group A (Mg group), in which patients were given magnesium citrate orally at a dosage of 610 mg every other day for 2 months and group B (control group), in which patients received only calcium acetate therapy as a phosphate binder. At baseline and 2 months later, all patients underwent a carotid artery ultrasound scan to measure carotid IMT.

RESULTS: At the end of 2 months, mean serum calcium, phosphorus, and calcium x phosphorus product were not changed in both groups. As expected, mean serum Mg level significantly increased in the Mg group at the end of 2 months. In addition, serum parathyroid hormone (PTH) level significantly decreased in the Mg group at the end of 2 months (P = 0.003). Baseline carotid IMT was similar between the groups. Bilateral carotid IMT was significantly improved in patients treated with magnesium citrate compared to initial values (P = 0.001 for left, P = 0.002 for right).

CONCLUSION: Based on the present data, magnesium may play an important protective role in the progression of atherosclerosis in patients on dialysis. Further studies are needed to assess more accurately the role of magnesium in atherosclerotic regression in dialysis patients.

PMID: 18568412 [PubMed - as supplied by publisher]

http://www.docguide.com/news/content.ns ... s=18568412

[J.Lilinoe]

Thanks Seymore. I wish my cousin who is on dialysis could see the benefit of many supplements including magnesium.

[Seymore Spectacles]

Do you think your cousin might be willing to eat some magnesium-rich foods? Pumpkin seeds are an excellent source of magnesium, for instance.

http://www.whfoods.com/genpage.php?tnam ... nt&dbid=75

[Ralph Lotz]

I have found this website to be the best for magnesium information:
http://www.mgwater.com/

Paul Mason maintains this site. He owns Adobe Springs, one of the best sources of magnesium rich water in the world. Unfortunately the water is only readily available in California.
Other magnesium rich waters include Apollinaris from Germany and Radenska from Slovenia.

As many as 3 out of 4 may be magnesium deficient.
There are many good magnesium supplements available. Magnesium oxide is a poor choice.