Page 1 of 1

Interesting study: CBDA and CBGA (i.e. cannabis) bind to spike protein, prevent infection

Posted: Wed Jan 12, 2022 9:30 am
by johnyascorbate
https://pubmed.ncbi.nlm.nih.gov/35007072/
https://www.news-medical.net/news/20220111/Hemp-compounds-show-ability-to-prevent-the-entry-of-SARS-CoV-2-into-cells.aspx

Van Breemen and collaborators, including scientists at Oregon Health & Science University, found that a pair of cannabinoid acids bind to the SARS-CoV-2 spike protein, blocking a critical step in the process the virus uses to infect people.

The compounds are cannabigerolic acid, or CBGA, and cannabidiolic acid, CBDA, and the spike protein is the same drug target used in COVID-19 vaccines and antibody therapy. A drug target is any molecule critical to the process a disease follows, meaning its disruption can thwart infection or disease progression.

Re: Interesting study: CBDA and CBGA from hemp bind to spike protein, prevent infection

Posted: Wed Jan 12, 2022 1:26 pm
by ofonorow
And I was just about to post https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987002/

Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response