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Does oral asorbic acid interfere with systemic enzymes?

Posted: Sat May 06, 2023 9:04 am
by Telefunk
I've been taking nattokinase for circulatory health as well as digestive enzymes with meals. I wonder how oral ascorbic acid (AA) interacts with oral enzymes. I found this study that found AA inhibits amylase.

Inhibitory Effect of Ascorbic Acid on in vitro Enzymatic Digestion of Raw and Cooked Starches
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662378/

I try to take the AA separately from nattokinase but they both are best on an empty stomach (I do an ascorbate flush weekly). I wonder how long apart they should be spaced, if at all.

Re: Does oral asorbic acid interfere with systemic enzymes?

Posted: Thu Jun 08, 2023 2:23 pm
by ofonorow
A major implication of such inhibition is a slowed rate of starch digestion into glucose, which thereby reduces postprandial hyperglycemia


interfere doesn't seem to be the appropriate word. I read this showing ascorbic slows down the production of glucose, a good thing.