Cancel a second stent or no?

The discussion of the Linus Pauling vitamin C/lysine invention for chronic scurvy

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Blanko
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Re: Cancel a second stent or no?

Post by Blanko » Wed Jun 19, 2024 7:33 pm

Felt good today despite not much sleep. I think I just need to be more careful to use the magnesium at night sparingly. Can't take more thinking it's going to knock me out. Has a U curve effect I believe, similar to melatonin and alcohol, where you want to ensure you don't overdo it.

Ideally I would want something that helps me sleep a great deal to really heal and repair my body, which is what I was hoping the magnesium would facilitate since the night prior with such excellent sleep I was able to sleep and sleep and woke up drowsy such that I was able to sleep still more. That's what I'm looking for right now to best heal and rejuvenate my body.

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Re: Cancel a second stent or no?

Post by Blanko » Thu Jun 20, 2024 12:19 am

Here's an interesting anecdote:

"that's interesting. I've tried several forms of magnesium and they've all given me insomnia. Or rather feeling like I'm constantly on the surface of sleep and never quite asleep. I'll give it a shot."

"Completely agree and that’s a great articulation of it."

Found that here on a thread saying B1 and magnesium work together and antagonize each other: https://www.reddit.com/r/Nootropics/com ... ts_taking/

May be ideal to take dark cacao earlier in the day, which has mild stimulant properties, and count on that to feed the body with the extra magnesium it needs?

I do recall when I would take dark cacao in the evenings even though I would stay up later, slightly stimulated, I slept really well when I finally got to sleep.

Currently took 1 of my Metagenics threonate some time ago, feel sleepy, and expect I should sleep well, but I've also read threonate can cause bad withdrawal symptoms.

For example: "Hey. I’ve been feeling like I’m literally dying. Like my brain is dying after I’ve stopped taking Mag L Threonate.

Nothing has changed in my life besides stopping taking this supplement. I’m absolutely freaked out. Definitely an increase in anxiety, and an increase in depression, but just feeling like I’m dying."

Therefore, I don't want to make it a staple in my life and will not buy more once I finish this bottle. This bottle I will use sparingly and with due respect to avoid issues as best I can.

Some other experiences at the linked thread:

"I only used one bottle and got horrible insomnia for a week afterwards. This was years ago before much information was available. I wasn't mag deficient, as I was taking a blend (in one capsule) daily for a year prior. I suspect this is due to L-threonate being high in BBB permeability."

"I actually didn't even know one could suffer withdrawals from it, until I ran out a month or so ago and forgot to order more. My anxiety around my time of PMS was horrible and I could not figure out why.. ditto with waking up throughout the night, like 2-3x times a night with NO reasoning. I just found some reddits while looking up the best brand to reorder and came across withdrawals and I was like holy sh**, this is what I had been experiencing this past month."

"I’ve been taking it for only like a week. Stopped yesterday, last night proceeded to have such bad anxiety I thought I was going crazy. Very interesting stuff."

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Re: Cancel a second stent or no?

Post by Blanko » Thu Jun 20, 2024 12:27 pm

Just an update. Turns out I had insomnia despite feeling sleepy. Couldn't sleep. As a last resort took a B complex with 1 magnesium glycinate, and had a great sleep. Seems like you need extra B1 or B vitamins if supplementing with magnesium.

Magnesium Intolerance? Consider Thiamine (Vitamin B1):

https://www.youtube.com/watch?app=desktop&v=pBxWivhBdpA

Could be the magic combination. From not being able to sleep to sleeping great. I'll see over the coming days if it works consistently.

Presumably B Complex should be taken early in the day and the mag at night.

I had been off my B Complex because I thought it was making me feel more tense during the days.

Forgot to add I took .5 mg of melatonin, which also may have helped. I use melatonin only sparingly since it only works well for me when I use it only when needed vs thinking it is a nightly sleep aid.

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Re: Cancel a second stent or no?

Post by pamojja » Thu Jun 20, 2024 3:54 pm

Just read this: "At least 400mg magnesium, personally with severe deficiency took in average 1.8g daily for the last 14 years."

Did you need extra B1 to tolerate that? What were you experiencing before that high mag supplementation and how did it fix those issues? Are you sure you needed so much?
I knew I was severely deficient by excruciating painful muscle cramps, and of course by repeated whole-blood magnesium tests. I always followed the advice of Pauling, and supplemented with plenty of B vitamins too. 2 years mega dosing up to 1,6 g/d vitamin B1 didn't make any further difference.

Supplemental Mg, even at 1.8 g/d elemental now for more than 15 years, alleviated painful muscle cramps only somewhat. Finally, only regular Mg-sulfate IVs ceased the cramps, though still remained deficient in whole-blood tests.

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Re: Cancel a second stent or no?

Post by Blanko » Thu Jun 20, 2024 5:12 pm

What do you think caused your severe muscle cramps condition?

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Re: Cancel a second stent or no?

Post by pamojja » Fri Jun 21, 2024 4:52 am

I suspect many subclinical nutrient deficiencies before starting to supplement. Some indication of them already at birth (slight pectus excavatum), really many diseases which would greatly increase nutrient needs, a 10-year 3rd-world travel with often only very deficient food availability (rice and beans, or tortillas i frijoles..).

The only nutrient repleted, which has a high metabolic need of co-factor Mg, would be Vitamin D3. Therefore, repletion with Vitamin D3 might have pushed a lifelong subclinical deficiency into very severe. Which usually recommended amounts of Mg in the beginning of supplementation could no more prevent.

There are other possibilities. Due to biochemical individuality and complex health-history, something in Mg-absorption, retention and metabolism might be simply malfunctioning. That's why I always would also use blood-testing. 99% of the population might be Mg deficient, but oneself might be one with a metabolic error and overload. And therefore a rare case susceptible to tachycardia from Mg.


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