INTRAVENOUS VITAMIN C PRIMERS
Dr. Robert Cathcart II, MD: Preparation of Vitamin C for IV Use Video
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Foundation's updated version of Dr. Cathcart's written IV/C prep instructions: http://www.vitamincfoundation.org/pdfs/civprep.pdf
Cathcart's original instructions: https://vitamincfoundation.org/www.orthomed.com/civprep.htm
GENERAL PRINCIPLES
AA versus SA
The common mistake is to use Ascorbic Acid rather than sodium ascorbate for the IV/C. (Dr. Cathcart felt this is because the early Dr. Frederick Klenner, MD, papers used the term "ascorbic acid.") Note: It is possible to use a buffered ascorbic acid, but the pH must be verified to be at least 7.1. The story of a large off-shore clinic who ruined a woman's veins using ascorbic acid: https://vitamincfoundation.com/forum/viewtopic.php?f=10&t=7563
Shelf Life
The commercial IV/C vials may degrade and do not have the same therapeutic value as sodium ascorbate "made fresh" to Dr. Cathcart's specification's. (See IV/C Primer links above)
Personal experience: It required some convincing before a local doctor would believe there was any difference between a standard commercial vial and the Cathcart sodium ascorbate method. However, after seeing the effect for himself on several patients, he switched to the Cathcart (sodium ascorbate) approach. (At first, he obtained the sodium ascorbate from a Compounding Pharmacy, but now mixes it fresh just prior to the IV/C) . One of his patients was a former patient of Dr. Cathcart, and reported that the IV/C that he had been getting from this doctor (from the commercial vials) were nothing like what he received from Dr. Cathcart. After the switch to sodium ascorbate, the IV/C he receives with the sodium ascorbate IV/Cs are more like he remembered.
CANCER
While Dr. Levy has found clinically that a 50 gram IV/C is general dosage that works for most conditions for most people, the use if IV/C treatment for cancer changes that ball game - both in quantity and duration (drip speed). The Riordan clinic's recomendations are discussed in this topic:
https://vitamincfoundation.com/forum/viewtopic.php?f=7&t=12870&p=45939&hilit=jacquie#p45939
We gave a series of vitamin C infusions to a 72 year old male who was in excellent physical condition except for slowly progressing, non-metastatic carcinoma of the prostate...From this experiment we observed that a 30 gram infusion was not adequate to raise plasma levels of vitamin C to a level that was toxic to tumor cells (>200 mg/dL for dense monolayers and >400 mg/dL for hollow fiber models). Infusion of 60 grams resulted in a brief (30 min) elevation of plasma levels of vitamin C above 400 mg/dL, while 60 grams infused over 60 minutes immediately followed by 20 grams infused over the next 60 minutes resulted in a 240 minute period in which the vitamin C plasma concentration was near or above 400 mg/dL
Even Dr. Cathcart relied mainly on oral vitamin C for his patients. Note, orally Dr. Cathcart recommended Ascorbic Acid over any mineral ascorbate, even sodium ascorbate. Dr. Cathcart's paper on oral dosing of ascorbic acid to bowel tolerance: https://vitamincfoundation.org/www.orthomed.com/titrate.htm
The Foundation's own research has added support to Cathcarts belief. Ascorbic acid orally behaves differently than sodium ascorbate orally. Ascorbic Acid ORALLY can create blood levels that exceed IV/C for a short duration (i.e. the first fifteen minutes.) Our paper has been accepted and is awaiting publication at the Journal of Orthomolecular Medicine.
If you have questions regarding specific applications of IV/C, e.g. cancer or infectious disease, please post to the appropriate forum.