This morning I called your Vitamin C Foundation(tel. 800-894-9025) and a was asked to contact you directly to your personal email.
My name is Cesar [delted] I am a naturopathic doctor practicing in Lima Peru.
I own a compounding pharmaceutical company here and we are working on a standardized Vitamin for mega doses through IV therapy.
Our first attempt was with:
two presentations:
Dosis No. 1 50ML X 15grams in 50 ML amber vial
15 grams of ascorbic Acid
50 ml of Sterile water for Injections (WFI)
Dosis No. 2 50ML X 7.5grams in 50 ML amber vial
7.5 grams of ascorbic Acid
50 ml of Sterile water for Injections (WFI)
Results:
Patient : Male 55years
Dosis Number 2 was diluted 250 ML sodium ringer
Treatment Protocol:
The patient's
vitamin C treatment protocol was 30 grams of
vitamin C in 250 mL of Ringer's Lactate given by
intravenous injection (40 drops per minute)
Patient did not tolerate the drip. was to painful. in pain scale of 1-10 (10 highest) patient complained of burning sensation and pain at 10. Treatment was discontinued and no attempt of Dosis 1 (50ML X 15 grams of Ascorbic Acid) was tried.
Doctor then attempted with a second patient but added 10% Sodium Bicarbonate but was still painful , Pain was now rated at 7-8.
Doctor then attempted with a same second patient but added 10% Sodium Bicarbonate and 1% procaine hydrochloride. The treatment was now well tolerated by the patient.
Both patients have tolerated IV therapy with competitors Vitamin C preparation.
Owen, after seeing your website last night, I conclude that we were burning the patient. I came in ant tested the Ph of Dosis No. 2 at 2.3
I concluded that he had to reformulate . Today I did the following:
100 ML of water ( WFI)
15 grams of ascorbic acid
6 grams of Sodium Bicarbonate
This product has a PH of 5.9 - 6
Do you think this new formulation would work or should we just stop using Ascorbic Acid and use what you recommend Sodium ascorbate.
If so would this formulation be the correct one.
100 ML of water (WFI)
15 grams of Sodium ascorbate
to produce 2 vials of 50ML with 7.5grams of Vitamin C
Or would I have to add a buffer to reduce ph.
Please help us.
Best regards,