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For me, the dosage of vitamin D3 you are taking is higher than I would recommend or than I would take myself, as are your resulting blood levels. So in a way we are in violent agreement. I just object to the word "toxicity" being used with respect to any vitamin without qualifications
I am interested whether you ever get colds during the winter (whether your high blood levels are protective.)
And I assume you are taking vitamins K and A to balance your high levels, correct?
johnyascorbate wrote:Vitamin A is a Vitamin K antagonist when taken in "large doses," and when taken in excessive amounts Vitamin A can cause hemorrhage. For those of use who do take both Vitamin K and Vitamin A either from a multi-vitamin or in separate supplement form, I believe the extra Vitamin A is canceling out the Vitamin K we are taking as well. Can anybody at the forum shed some more light on this interaction?
vitamin A might do more harm than good. In an analysis of studies, taking vitamin A supplements alone or in combination with other antioxidants is associated with an increased risk of mortality from all causes (15305).
Antioxidant Combo Decreases Smokers' Cancer Risk ...
NEW LOOK, OLD FINNISH DATA! contradicts long held and widely reported belief that beta carotene increases cancer risk in smokers...
In the 'new' study, researchers from Yale University and other US institutes together with colleagues from the National Public Health Institute in Helsinki, Finland analysed the same data but looked at the total intake of antioxidants, including selenium, vitamin E, vitamin C as well as carotenoids and flavonoids, rather than one single antioxidant.
The researchers report that smokers in the top quintile of dietary antioxidant intake had a 16 per cent lower risk of lung cancer compared to those with the lowest intake.
Smokers who ate large amounts of meat had a 25 per cent decrease, despite red meat having a high oxidative effect.
The results counter the earlier findings of the Finnish ATBC study, carried out in the 90s, which found an increased risk of the disease for smokers with high beta-carotene intake.
I am still confused (which seems to be an all too recurring condition for me these days). Where in this paragraph does it say anything about vitamin A and bleeding?
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism (505). High doses of vitamin A could increase the risk of bleeding with warfarin. Advise patients taking warfarin to avoid doses of vitamin A above the Tolerable Upper Intake Level of 10,000 units/day for adults.
Large doses of vitamin A and vitamin E have been found to antagonize vitamin K (8). Excess vitamin A appears to interfere with vitamin K absorption, whereas vitamin E may inhibit vitamin K-dependent carboxylase activity and interfere with the coagulation cascade (99).
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