Japanese trial with 500 mg daily
Posted: Thu Oct 19, 2006 5:45 am
Hi everybody,
I think that we have not discussed recently published peer-reviewed article:
S Sasazuki et al.,
European Journal of Clinical Nutrition (2006) 60, 9–17.
Effect of vitamin C on common cold: randomized controlled trial.
http://www.nature.com/ejcn/journal/v60/n1/abs/1602261a.html
Even though the authors compared 50 mg vs. 500 mg daily (single dose),
they prove significantly lower incidence of colds in what they call "high-dose"
group (we think it's not high, aren't we?).
The conclusion that duration of symptoms is even longer in "high-dose"
group is flawed - they check how long the nose is runny. Of course, the
reduced viscosity of nasal liquid is the logical explanation - this is one of
the tricks which leaves the nose open.
Linus Pauling is neither cited nor mentioned in this article, but nevertheless,
finally it is possible to publish in high-rated journal that he was right about
prevention of the common cold. The pharmacokinets is taken from the
flawed research (Levine's lab, 1996, instead what came from the same lab
in 2004.).
I think that we have not discussed recently published peer-reviewed article:
S Sasazuki et al.,
European Journal of Clinical Nutrition (2006) 60, 9–17.
Effect of vitamin C on common cold: randomized controlled trial.
http://www.nature.com/ejcn/journal/v60/n1/abs/1602261a.html
Even though the authors compared 50 mg vs. 500 mg daily (single dose),
they prove significantly lower incidence of colds in what they call "high-dose"
group (we think it's not high, aren't we?).
The conclusion that duration of symptoms is even longer in "high-dose"
group is flawed - they check how long the nose is runny. Of course, the
reduced viscosity of nasal liquid is the logical explanation - this is one of
the tricks which leaves the nose open.
Linus Pauling is neither cited nor mentioned in this article, but nevertheless,
finally it is possible to publish in high-rated journal that he was right about
prevention of the common cold. The pharmacokinets is taken from the
flawed research (Levine's lab, 1996, instead what came from the same lab
in 2004.).