Personally was prescribed aspirin and statin. After finding out that statins taken for 5 years with prior heart attack only reduce in 1 out of 84 patients 5-year mortality, and aspirin only in 1 out of 330. No longer term data. I never looked back.
http://www.thennt.com/home-nnt/ Better don't ask me about prescription meds, because with the little I know of them I wouldn't take.
This comes up for Brilinta on wikipedia:
https://en.wikipedia.org/wiki/Ticagrelor
Adverse effects
The most common side effects are shortness of breath (dyspnea, 14%)[11] and various types of bleeding, such as hematoma, nosebleed, gastrointestinal, subcutaneous or dermal bleeding. Ventricular pauses of 3 seconds occur in 5 percent of people in the first week of treatment. Ticagrelor should be administered with caution or avoided in patients with advanced sinoauricular disease.[12] Allergic skin reactions such as rash and itching have been observed in less than 1% of patients.[5]
Interactions
Inhibitors of the liver enzyme CYP3A4, such as ketoconazole and possibly grapefruit juice, increase blood plasma levels of ticagrelor and consequently can lead to bleeding and other adverse effects. Conversely, drugs that are metabolized by CYP3A4, for example simvastatin, show increased plasma levels and more side effects if combined with ticagrelor. CYP3A4 inductors, for example rifampicin and possibly St. John's wort, can reduce the effectiveness of ticagrelor. There is no evidence for interactions via CYP2C9.
The drug also inhibits P-glycoprotein (P-gp), leading to increased plasma levels of digoxin, ciclosporin and other P-gp substrates. Levels of ticagrelor and AR-C124910XX (the active metabolite of ticagrelor formed by O-deethylation[13]) are not significantly influenced by P-gp inhibitors.[5]
In the US a boxed warning states that use of ticagrelor with aspirin doses exceeding 100 mg/day decreases the effectiveness of the medication.[14]
For example, I take dozens of blood-thining supplements. But only with one Baby-aspirin I do get instant bloody stool. So the question to me would rather be if Belinda is safe on its own?
Inosine isn't even a blood-thinner, or liver-enzyme inhibitor. However, it raises uric acid, and too high levels of uric acid would come with the risk of gout, which is just as bad as low levels.
https://selfhacked.com/blog/uric-acid-c ... ly-causal/