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Vitamin C doesn't lower Lp(a)! DUH!

Posted: Sat May 12, 2012 6:58 am
by Johnwen
I was doing some research on Endothiel dysfunction and came across this abstract from 1997
They actually used 4.5 Grams of V-C but it didn't lower LP(a). DUH! Imagine if they would have added about 4 Grams of L-lysine. It probably would have been swept under the rug because it worked too good!
They didn't say if anyone died during the study either!!


http://www.ncbi.nlm.nih.gov/pubmed/7479198

Re: Vitamin C doesn't lower Lp(a)! DUH!

Posted: Tue May 15, 2012 2:52 am
by ofonorow
I communicated with Dr. Bostom after this was published, and that was about the conclusion I drew. That 4-5 g of vitamin C does not affect Lp(a) during the period studied - 12 weeks.

Assuming they measured Lp(a), etc.

It is interesting that their conclusion regarding Lp(a) is not iron clad. If my memory serves, this finding
could be in error about 40% of the time, correct?
Multiple linear regression analysis revealed no significant effect of supplementation on postintervention Lp(a) levels (p = 0.39) in a model that included treatment group assignment, and baseline Lp(a) levels.


Can you get into the study to see the actual data? One would expect about a 30% drop in Lp(a), but I am not certain of the period required.