I've been taking nattokinase for circulatory health as well as digestive enzymes with meals. I wonder how oral ascorbic acid (AA) interacts with oral enzymes. I found this study that found AA inhibits amylase.
Inhibitory Effect of Ascorbic Acid on in vitro Enzymatic Digestion of Raw and Cooked Starches
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662378/
I try to take the AA separately from nattokinase but they both are best on an empty stomach (I do an ascorbate flush weekly). I wonder how long apart they should be spaced, if at all.