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by ofonorow » Wed Jan 09, 2019 5:42 am
Thanks to the book NIACIN: THE REAL STORY, by Hoffer, Saul, et. al., taking the right amount of Niacin is important, whether or not it provides any other added benefits visa via Lp(a) and heart disease.
Hoffer used to match his vitamin C and Niacin dosage recommendations (from his other books.) In his book about Cancer and Vitamin C, which is a collection of case reports, I believe his general recommendations were 6 g ascorbate and 6 g niacin.
For those readers who don't know, it was Hoffer's book on using high doses of Niacin to treat schizophrenia that opened the eyes of Linus Pauling, creating his interest that led to orthomolecular medicine. How, Pauling wondered, could a substance that was so physiologically powerful that a spec could cure a deficiency disease, e.g. pellegra, be taken at doses several orders of magnitude larger (e.g. 18 grams) and not have any toxic effects?
Hoffer explains his theory in NIACIN: THE REAL STORY, i.e., that perhaps 1/3 of the population has a genetic defect that causes mental problems, and that some dosage of Niacin corrects.
Owen R. Fonorow
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