Vitamin C supplementation improves placental function and alters placental gene expression in smokers

[ofonorow]

https://www.nature.com/articles/s41598-024-73005-7

While the clinical impact of the observed placental function changes on fetal development and obstetric outcome is unknown, this finding, combined with the transcriptomic results, suggests that perturbations to fetal hemodynamics by MSDP may be ameliorated by vitamin C supplementation. This supports the findings of our prior studies highlighting the benefits of vitamin C supplementation to mitigate some aspects of offspring morbidity, particularly respiratory morbidity, in pregnancies where abstaining from nicotine products is not feasible.